A Groundbreaking Initiative in Understanding Pregnancy Loss Perelel Joins Forces to Support the HOPE Project

By Ruthie Friedlander

In a profound step towards unraveling the mysteries of pregnancy loss, our friends at Perelel have proudly partnered to support the HOPE Project, a pioneering research initiative. This collaboration aligns seamlessly with Perelel’s founding mission: to ensure everyone has the right to a healthful pregnancy. As the community around this mission expands, so does the commitment to understanding and supporting the full spectrum of the pregnancy journey, including its most challenging aspects

As we at Babe know all too well, pregnancy loss is a deeply personal and often isolating experience, touching 15% of pregnancies. Despite its prevalence, there’s a staggering lack of clinical research and understanding in this area. The HOPE Project, driven by leading institutions like Stanford University School of Medicine, University of California, San Francisco, and Oregon Health & Science University, aims to change this narrative.

The initiative’s primary goal is to build the most comprehensive and inclusive participant registry to date. This registry is critical in aiding the research to uncover potential causes of pregnancy loss, enabling better prediction and management of pregnancy outcomes in the future.

The success of this study hinges on community involvement. The call to action is clear: spread awareness and encourage eligible individuals to contribute to this transformative research. Eligibility extends to anyone who has experienced pregnancy loss, regardless of gender identity, sexual orientation, race, ethnicity, or couple status.

The HOPE Project aims to enroll 4000 participants by 2026, marking a significant stride towards understanding pregnancy loss at a clinical level. The focus is not only on genetic profiling of trios (mom, dad, and past pregnancy) but also on identifying gene pathways essential to human development. Currently, while over 3000 human genes are believed to be crucial for early development, there’s minimal knowledge about their impact on recurrent pregnancy loss.

Navigating the waters of pregnancy loss can be daunting and often, heartbreaking. Through the HOPE Project, Perelel and other participating partners are dedicated to shedding light on this sensitive, yet vital topic, offering hope and answers to parents-to-be. By joining hands in this endeavor, we can empower individuals with the knowledge and support they need to navigate their journey to parenthood with greater understanding and hope.